Abnormal permeability precedes the development of a gluten sensitive enteropathy in Irish setter dogs.
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چکیده
منابع مشابه
Abnormal permeability precedes the development of a gluten sensitive enteropathy in Irish setter dogs.
Intestinal permeability to 51Cr-EDTA was examined during the development of gluten sensitive enteropathy in dogs bred from affected Irish setters and reared on a normal wheat containing diet. Comparisons were made with litter mates reared on a gluten free diet and with a control group of age matched, clinically healthy Irish setters reared on the normal diet. Studies at 4, 6, 8, and 12 months o...
متن کاملDietary modulation of gluten sensitivity in a naturally occurring enteropathy of Irish setter dogs.
Gluten sensitivity in a naturally occurring enteropathy of Irish setter dogs, and the effects of excluding dietary cereal from birth on the subsequent response to gluten challenge were investigated. Peroral jejunal biopsy specimens were obtained at 1 year of age for morphometric and biochemical examinations, and intestinal permeability was assessed using 51Cr-ethylenediaminetetraacetic acid. Af...
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The intestinal mucosa of patients with gluten-sensitive enteropathy responds to gluten challenge in vivo with a striking increase in IgA and IgM synthesis. Whether this increase in immunoglobulin synthesis is due in some part to the production of antigliadin antibodies is examined. Using an affinity chromatography technique it has been demonstrated that in six of seven patients with gluten-sens...
متن کاملA stable isotope study of zinc kinetics in Irish setters with gluten-sensitive enteropathy.
The short-term kinetics of Zn turnover were studied in Irish setters with gluten-sensitive enteropathy and control dogs following intravenous injection of 0.25 mg 96.5% enriched 70ZnCl2. The 70Zn enrichment of serum was found closely to obey two-compartment kinetics and the derived two-compartment decay equation was used to calculate the size and turnover of the two initial rapidly exchanging p...
متن کاملThe existence of inflammatory bowel lesions in gluten-sensitive enteropathy.
Three patients with coincident coeliac disease and inflammatory bowel disease are described. In 2 patients with known coeliac disease the recurrence of diarrhoea was not due to dietary deviation but to an additional large bowel pathology.
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ژورنال
عنوان ژورنال: Gut
سال: 1991
ISSN: 0017-5749
DOI: 10.1136/gut.32.7.749